- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
Nifetepimine is a dihydropyrimidone calcium channel blocker that down-modulates SERCA3 (sarco/endoplasmic reticulum Ca2+ -ATPase 3) pump, and protects of the CD4+ T cells from tumor-induced apoptosis. Nifetepimine induces apoptotic cell death in triple negative breast cancer (TNBC) cells by stimulation of cross-talk between ER stress and the MEK/ERK pathway.
Nifetepimine is a dihydropyrimidone calcium channel blocker.
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 10 mg/mL, clear |
| web metadata keyword.default | CAS 110448-29-8 Nifetepimine,Nif,Nifetepimine Sigma-Aldrich,Nifetepimine |
| storage temp. | 2-8°C |
| SMILES string | O=C(OCC)C1=C(C)NC(NC1C2=CC([N+]([O-])=O)=CC=C2)=O |
| InChI | 1S/C14H15N3O5/c1-3-22-13(18)11-8(2)15-14(19)16-12(11)9-5-4-6-10(7-9)17(20)21/h4-7,12H,3H2,1-2H3,(H2,15,16,19) |
| InChI key | PPBNQKLDXXHPMH-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 4164.19
-
¥ 1451.54
-
¥ 5887.85
-
询价
-
询价
-
¥ 3442.25
-
¥ 9737.84
-
询价
-
¥ 238.17
-
¥ 6330.00
-
¥ 10277.12
-
¥ 1196.14
-
¥ 4020.77
-
¥ 3404.94
-
¥ 2452.91
-
¥ 66743.99
-
¥ 70526.15
-
¥ 21144.84
-
¥ 390328.90
-
询价
微信小程序
7X24小时在线咨询