Besifloxacin hydrochloride,50MG,SML1608-50MG,Sigma

销售价: ¥ 4216.24 / 件
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订货号 0BT1294
品牌型号 Sigma SML1608-50MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Besifloxacin stops the production of pro-inflammatory cytokines in vitro.
Besifloxacin is a broad spectrum fourth-generation fluoroquinolone antibiotic.
Besifloxacin is a broad spectrum fourth-generation fluoroquinolone antibiotic. Besifloxacin is effective against gram positive and negative, aerobic and anerobic bacteria. Fluoroquinolones stabilize DNA strand breaks created by DNA gyrase and topoisomerase IV by binding to the enzyme-DNA complex generating persistent, covalent enzyme–DNA adducts, inhibiting DNA synthesis. Besifloxacin inhibits both DNA gyrase and topoisomerase IV at nearly equal concentrations. It is used clinically primarily in the treatment of bacterial conjunctivitis.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
storage conditiondesiccated
color white to light brown
solubilityDMSO: 2 mg/mL, clear (warmed)
storage temp.−20°C
SMILES string[H]Cl.OC(C1=CN(C2CC2)C3=C(Cl)C(N4CCCCC(N)C4)=C(F)C=C3C1=O)=O
InChI1S/C19H21ClFN3O3.ClH/c20-15-16-12(18(25)13(19(26)27)9-24(16)11-4-5-11)7-14(21)17(15)23-6-2-1-3-10(22)8-23;/h7,9-11H,1-6,8,22H2,(H,26,27);1H
InChI keyPMQBICKXAAKXAY-UHFFFAOYSA-N
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