Intronistat B hydrobromide，25MG，SML2630-25MG，Sigma

Biochem/physiol Actions

Inhibitor of the self-splicing group IIB intron found in fungi
Intronistat B is a potent inhibitor of the self-splicing group IIB intron, a mitochondrial RNA tertiary structure necessary for respiration in fungi, yeast and plants, but not found in vertebrates. Intronistat B was found to have antifungal activity comparable to that of amphotericin B in inhibiting growth of the Candida parapsilosis. It did not inhibit spliceosomal processing, group I intron splicing or splicing of group II introns from subclasses other than subclass IIB and was not toxic to human cells.