Efonidipine hydrochloride monoethanolate,5MG,E0159-5MG,Sigma

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订货号 0BT4108
品牌型号 Sigma E0159-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Efonidipine hydrochloride is a racemic compound that has some L-type as well as T-type calcium channel blocking activity.
Racemic efonidipine has both L-type and T-type calcium channel blocking activity. The R(−)-isomer appears to be very selective for T-type calcium channel. The S(+)-isomer inhibits the expressed Ca(V)1.2, Ca(V)1.3 and Ca(V)3.1 channel currents almost equally.


Features and Benefits

This compound was developed by Shionogi. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


技术参数 Specifications
assay≥98% (HPLC)
formpowder
storage conditiondesiccated
colorpale yellow
solubilityDMSO: >5 mg/mL,H2O: insoluble
originatorShionogi
storage temp.2-8°C
SMILES stringCl.CCO.CC1=C(C(c2cccc(c2)[N+]([O-])=O)C(=C(C)N1)P3(=O)OCC(C)(C)CO3)C(=O)OCCN(Cc4ccccc4)c5ccccc5
InChI1S/C34H38N3O7P.C2H6O.ClH/c1-24-30(33(38)42-19-18-36(28-15-9-6-10-16-28)21-26-12-7-5-8-13-26)31(27-14-11-17-29(20-27)37(39)40)32(25(2)35-24)45(41)43-22-34(3,4)23-44-45;1-2-3;/h5-17,20,31,35H,18-19,21-23H2,1-4H3;3H,2H2,1H3;1H
InChI keyIKBJGZQVVVXCEQ-UHFFFAOYSA-N
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