Anti-CCL7 antibody produced in rabbit，100UL，AV07048-100UL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

CCL7, also known as MCP3, is a CC chemokine that binds monocytes and has been shown to regulate macrophage activity.

Immunogen

The immunogen for anti-CCL7 antibody: synthetic peptide derected towards the N terminal of human CCL7

Application

Anti-CCL7 antibody produced in rabbit is suitable for western blotting at a concentration of 0.5 μg/ml. For immunohistochemistry of paraffin-embedded tissue sections, a concentration of 4-8 μg/ml is suitable.

Biochem/physiol Actions

CCL7 encodes monocyte chemotactic protein 3, a secreted chemokine which attracts macrophages during inflammation and metastasis. It is a member of the C-C subfamily of chemokines which are characterized by having two adjacent cysteine residues. The protein is an in vivo substrate of matrix metalloproteinase 2, an enzyme which degrades components of the extracellular matrix. This gene is part of a cluster of C-C chemokine family members on chromosome 17q.

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Other Notes

Synthetic peptide located within the following region: TSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPT

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	9 kDa
species reactivity	pig, human
concentration	0.5 mg - 1 mg/mL
technique(s)	immunohistochemistry: suitable,western blot: suitable
NCBI accession no.	NP_006264
UniProt accession no.	P80098
shipped in	wet ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... CCL7(6354)

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