Garenoxacin mesylate monohydrate,50MG,SML1618-50MG,Sigma

销售价: ¥ 4363.28 / 件
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订货号 0BT5798
品牌型号 Sigma SML1618-50MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

Broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections
Garenoxacin is a broad spectrum fluoroquinolone antibiotic suitable for treatment of gram-positive and gram-negative bacterial infections. Garenoxacin has a low mutant prevention concentration and a narrow mutant selection window. Data shows that garenoxacin has anti-inflammatory properties. It significantly alleviates LPS-induced IL-8 production through the negative regulation of the ERK1/2 pathway both in the human airway epithelial cell line A549 and the monocyte cell line THP-1.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
storage conditiondesiccated
color white to beige
solubilityH2O: 10 mg/mL, clear (warmed)
storage temp.2-8°C
SMILES stringOC(C1=CN(C2CC2)C3=C(OC(F)F)C(C4=CC(CN[C@@H]5C)=C5C=C4)=CC=C3C1=O)=O.CS(=O)(O)=O.[H]O[H]
InChI1S/C23H20F2N2O4.CH4O3S.H2O/c1-11-15-5-2-12(8-13(15)9-26-11)16-6-7-17-19(21(16)31-23(24)25)27(14-3-4-14)10-18(20(17)28)22(29)30;1-5(2,3)4;/h2,5-8,10-11,14,23,26H,3-4,9H2,1H3,(H,29,30);1H3,(H,2,3,4);1H2/t11-;;/m1../s1
InChI keyIGTHEWGRXUAFKF-NVJADKKVSA-N
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