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Biochem/physiol Actions
IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures.
IC87201 is a potent inhibitor of the nNOS/PSD-95 protein-protein interaction that blocks NMDA-induced 3′ ,5′ -cyclic guanosine monophosphate (cGMP) production in hippocampal cultures. IC87201 exhibits analgesic properties in mice pain models. Contrary to NMDA receptor antagonists nNOS/PSD-95 protein-protein interaction inhibitors spared source memory, spatial memory, and motor function in rats.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to brown |
| solubility | DMSO: 5 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | Clc1c(c(cc(c1)Cl)CNc2cc3[nH]nnc3cc2)O |
| InChI | 1S/C13H10Cl2N4O/c14-8-3-7(13(20)10(15)4-8)6-16-9-1-2-11-12(5-9)18-19-17-11/h1-5,16,20H,6H2,(H,17,18,19) |
| InChI key | QEHVTUCLCBXQIC-UHFFFAOYSA-N |
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¥ 9207.92
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¥ 4173.75
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¥ 15214.65
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NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔
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¥ 67162.32
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