- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
MAC-545496 is a potent and selective inhibitor of glycopeptide-resistance-associated protein R (GraR) that displays antivirulence and antimicrobial adjuvant properties. MAC-545496 reverses β-lactam resistance in Methicillin-resistant strains (MRSA) and synergizes with cationic antimicrobial peptides (CAMPs). It also potentiates the effects of Cefuroxime and Oxacillin MRSA strains. MAC-545496 has no effect on commensal S. epidermidis and Gram-negative bacteria such as P. aeruginosa.
potent and selective inhibitor of glycopeptide-resistance-associated protein R (GraR); antivirulent, antibacterial
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | faint yellow to dark orange |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | S=C(Nc3ncc(cc3)Cl)NC(=O)c1cc(c(cc1)N2CCCCC2)[N+](=O)[O-] |
| InChI | 1S/C18H18ClN5O3S/c19-13-5-7-16(20-11-13)21-18(28)22-17(25)12-4-6-14(15(10-12)24(26)27)23-8-2-1-3-9-23/h4-7,10-11H,1-3,8-9H2,(H2,20,21,22,25,28) |
| InChI key | AFOKREIUUQFDNW-UHFFFAOYSA-N |
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¥ 2068.25
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¥ 8520.40
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瓶顶过滤器-500ml容量,MF75TM系列，聚苯乙烯外壳，75mmPES滤膜，孔径0.45um,适合瓶颈尺寸33mm，12/箱，295-3345，Nalgene，Thermofisher，赛默飞世尔¥ 1938.54
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