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产品介绍
Product Description
Biochem/physiol Actions
JNJ-63533054 is a potent and selective agonist of the orphan receptor hGPR139, a GPCR receptor expressed in the brain in circumventricular regions of the habenula and septum. JNJ-63533054 has an EC50 value of 16 nM, crosses the blood-brain barrier, and is orally available.
Potent and selective agonist of hGPR139 with an EC50 value of 16 nM
技术参数
Specifications
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D -89 to -99°, c = 1 in ethanol |
| color | white to beige |
| solubility | DMSO: 20 mg/mL, clear |
| storage temp. | room temp |
| SMILES string | Clc1cc(ccc1)C(=O)NCC(=O)N[C@@H](C)c2ccccc2 |
| InChI key | MWDVCHRYCKXEBY-LBPRGKRZSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
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