Rabbit anti-ARID4B Antibody, Affinity Purified,100UL,PLA0247-100UL,Sigma

销售价: ¥ 3650.33 / 件
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订货号 0BT7935
品牌型号 Sigma PLA0247-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Immunogen

The epitope recognized by PLA0247 maps to a region between residue 125 and 175 of human AT rich interactive domain 4B using the numbering given in entry NP_057458.4 (GeneID 51742).


Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


Other Notes

ARID4B (AT-rich interactive domain-containing protein 4B) is also known as RbBP1L1 (retinoblastoma binding protein 1-like 1) and is a retinoblastoma binding protein and member of the AT-rich interaction domain (ARID) family of proteins. In addition to the ARID DNA binding domain, ARID4B also contains a chromo domain and a TUDOR domain, indicating a function in chromatin organization and protein-protein interactions with methylated protein substrates. As a subunit of the SIN3A transcriptional co-repressor, ARID4B is implicated to be involved in chromatin remodeling and epigenetic modifications. ARID4B may play a role in the pathogenesis of breast cancer and other malignancies.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Segment100
conjugateunconjugated
antibody formaffinity purified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
species reactivityhuman
technique(s)immunohistochemistry: 1:1,000- 1:5,000,immunoprecipitation (IP): 5-10 μg/mg,western blot: 1:2,000- 1:10,000
accession no.NP_057458.4
UniProt accession no.Q4LE39
shipped inwet ice
storage temp.2-8°C
target post-translational modificationunmodified
Gene Informationrabbit ... ARID4B(51742)
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