5HPP-33,25MG,H9415-25MG,Sigma

销售价: ¥ 3764.43 / 件
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订货号 0BU1186
品牌型号 Sigma H9415-25MG
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最小订货量 1件
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产品介绍 Product Description

Biochem/physiol Actions

5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules.
5HPP-33 is a thalidomide derivative which was reported to be active as anticancer agent through stabilization of the microtubules. 5HPP-33 has shown inhibition of cell proliferation of both estrogen-dependent (MCF-7) and estrogen-independent (MDA-MB-231) breast cancer cells as well as other cell lines. A study in tubulin forming assay reported that 5HPP-33 acts as a microtubule formation inhibitor (IC50=810 nM).


技术参数 Specifications
assay≥98% (HPLC)
formsolid
color white to off-white
solubilityDMSO: >20 mg/mL
storage temp.2-8°C
SMILES stringCC(C)c1cccc(C(C)C)c1N2C(=O)c3ccc(O)cc3C2=O
InChI1S/C20H21NO3/c1-11(2)14-6-5-7-15(12(3)4)18(14)21-19(23)16-9-8-13(22)10-17(16)20(21)24/h5-12,22H,1-4H3
InChI keyLAKWINYVWJPHQW-UHFFFAOYSA-N
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