- 商品介绍
- 规格参数
- 包装参数
产品介绍
Product Description
Biochem/physiol Actions
Antagonist of NOP, the nociceptin/orphanin FQ (N/OFQ) receptor.
J-113397 is an antagonist of NOP, the nociceptin/orphanin FQ (N/OFQ) receptor. J-113397 exhibited an IC50 value of 2.3 nM in Chinese hamster ovary (CHO) cells expressing ORL1 receptor showed with 600-fold or less affinity for μ-, δ- and κ-opioid receptors.
技术参数
Specifications
| assay | ≥98% (HPLC) |
| form | powder |
| optical activity | [α]/D +7 to +10°, c = 1 in isopropanol |
| storage condition | desiccated |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | room temp |
| SMILES string | CCN1C2=CC=CC=C2N([C@H]3[C@H](CO)CN(CC4CCCCCCC4)CC3)C1=O |
| InChI | 1S/C24H37N3O2/c1-2-26-22-12-8-9-13-23(22)27(24(26)29)21-14-15-25(17-20(21)18-28)16-19-10-6-4-3-5-7-11-19/h8-9,12-13,19-21,28H,2-7,10-11,14-18H2,1H3/t20-,21+/m0/s1 |
| InChI key | MBGVUMXBUGIIBQ-LEWJYISDSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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