- 商品介绍
- 规格参数
- 包装参数
General description
Cathepsin G from human leukocytes is a neutral proteinase secreted by neutrophil granulocytes. It belongs to the family of serine proteases. Cathepsin G is a glycoprotein, which contains 1% carbohydrate. The gene is located on human chromosome 14q12.
Application
Cathepsin G from human leukocytes has been used to determine protease sensitivity. It has also been used for the stimulation and staining of dendritic cells and macrophage.
Biochem/physiol Actions
Cathepsin G from human leukocytes degrades various proteins, such as elastin, collagen, fibrinogen and immunoglobin. It may be implicated in muscle catabolism. Cathepsin G is involved in the activation or inactivation of protein hormones and the inactivation of plasma proteinase inhibitors. It alters the cytoskeleton, enhances the permeability of vascular endothelial cells and the chemotaxis of inflammatory cells. Cathepsin G is associated with autoimmunity and cancer. It exhibits chymotrypsin and trypsin like activity. Cathepsin G modulates neutrophil effector functions.
Cathepsin G has pro-apoptotic activity and can activate caspases in vitro.
Physical form
Lyophilized from 0.5 M pyridinium acetate, pH 5.3.
Other Notes
One unit will release one nanomole of p-nitroaniline per second from N-succinyl-Ala-Ala-Pro-Phe p-nitroanilide at pH 7.5 at 37 °C.
| biological source | human leucocytes |
| Quality Level | 200 |
| form | lyophilized powder |
| specific activity | ≥60 units/mg protein (Bradford) |
| mol wt | 23-30 kDa |
| UniProt accession no. | P08311 |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | human ... CTSG(1511) |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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¥ 1148.92
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¥ 4968.78
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¥ 1653.62
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无菌，PETG 方形有刻度培养基瓶，带盖，聚对苯二酸乙二醇酯共聚物，天然高密度聚乙烯盖，500毫升容量，每箱40，40/箱，342020-0500，Nalgene，Thermofisher，赛默飞世尔¥ 3684.34
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¥ 4404.38
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¥ 1351.48
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NALGENE 180透明塑料管，透明，柔软，多用，经济，内径 x 外径x壁厚，1/8 x 1/4 x 1/16，英寸，每箱数量50，50/箱，8000-0020，Thermofisher，赛默飞世尔
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¥ 44224.19
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