NCT-503 Inactive Control,25MG,SML1671-25MG,Sigma

销售价: ¥ 4363.28 / 件
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订货号 0BU5723
品牌型号 Sigma SML1671-25MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

NCT-503 Inactive Control has been used as a small molecule inhibitor of phosphoglycerate dehydrogenase in neuroblastoma cells.


Biochem/physiol Actions

NCT-503 Inactive Control is the inactive control probe for NCT-503, which is an inhibitor of phosphoglycerate dehydrogenase (PHGDH), the enzyme that catalyzes the first, rate-limiting step of glucose-derived serine synthesis. NCT-503 Inactive Control has an IC50 value >57 μM for PHGDH. NCT-503 has an IC50 value of 2.5 μM for PHGDH. NCT-503 Inactive Control is water soluble and has good stability, similar to NCT-503.
NCT-503 Inactive Control is the inactive control probe for NCT-503, which is an inhibitor of phosphoglycerate dehydrogenase (PHGDH).


Other Notes

The active PHGDH inhibitor, NCT-503, is available from Sigma. To learn more about and purchase NCT-503, click here.


技术参数 Specifications
Quality Segment100
assay≥98% (HPLC)
formpowder
color white to beige
solubilityDMSO: 5 mg/mL, clear (warmed)
storage temp.2-8°C
SMILES stringCC1=CC(NC(N2CCN(C3=CC=NC=C3)CC2)=S)=NC(C)=C1
InChI1S/C17H21N5S/c1-13-11-14(2)19-16(12-13)20-17(23)22-9-7-21(8-10-22)15-3-5-18-6-4-15/h3-6,11-12H,7-10H2,1-2H3,(H,19,20,23)
InChI keyITLPIAAGIQAGRA-UHFFFAOYSA-N
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