Pogostone，10MG，SML4198-10MG，Sigma

Application

Pogostone may be used:

• to study its insecticidal activity against Spodoptera litura (Fabricius) and Spodoptera exigua (Hübner)
• to study its effects on adipose tissue inflammation in vitro and in vivo
• to study its effects on osteolytic bone metastases in mice and investigate the molecular mechanisms of pogostone against cancer-induced osteoclast formation and cancer cell proliferation or migration in vitro

Biochem/physiol Actions

Pogostone is an active ingredient isolated from the essential oil of Pogostemon cablin (patchouli oil) that exhibits various pharmacological properties, including anti-inflammatory and anti-cancer activities. Pogostone attenuates high-fat diet–induced nonalcoholic fatty liver disease (NAFLD) in mice through inhibition of NLRP3 inflammasome signaling.