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- 规格参数
- 包装参数
Biochem/physiol Actions
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM) with greater than 50 fold selectivity over other mGluR subtypes. The EC50 values for human and rat mGlu4 are 240 and 110 nM, respectively, compared to greater than 10 mM for all other mGluRs.
VU0361737 is an mGluR4-specific positive allosteric modulator (PAM).
Features and Benefits
This compound is featured on the Glutamate Receptors (G Protein Family) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | film |
| color | white |
| solubility | DMSO: 15 mg/mL (clear solution) |
| storage temp. | 2-8°C |
| SMILES string | COc1cc(NC(=O)c2ccccn2)ccc1Cl |
| InChI | 1S/C13H11ClN2O2/c1-18-12-8-9(5-6-10(12)14)16-13(17)11-4-2-3-7-15-11/h2-8H,1H3,(H,16,17) |
| InChI key | ARYUXFNGXHNNDM-UHFFFAOYSA-N |
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