- 商品介绍
- 规格参数
- 包装参数
Application
Zotepine has been used as an anti-psychotic agent:
- in biophysical studies with serotonin 2A receptor (5-HT2AR)
- to study its effects on the inhibition of human organic cation transporter 1 (hOCT1)
- to study its protective effects on the human embryonic kidney (HEK cells)
Biochem/physiol Actions
Zotepine acts as an antagonist of dopamine D1, D2, and serotonin (5-HT2A/2C) receptors, and noradrenaline transporters. It shows therapeutic effects against schizophrenia and acute mania.
Zotepine is an atypical antipsychotic.
Features and Benefits
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
This compound was developed by Astellas. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
| assay | >98% (HPLC) |
| Quality Segment | 100 |
| form | powder |
| color | white to off-white |
| solubility | DMSO: ≥20 mg/mL |
| originator | Astellas |
| storage temp. | room temp |
| SMILES string | CN(C)CCOC1=Cc2ccccc2Sc3ccc(Cl)cc13 |
| InChI | 1S/C18H18ClNOS/c1-20(2)9-10-21-16-11-13-5-3-4-6-17(13)22-18-8-7-14(19)12-15(16)18/h3-8,11-12H,9-10H2,1-2H3 |
| InChI key | HDOZVRUNCMBHFH-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
询价
-
询价
-
询价
-
询价
-
¥ 3109.49
-
¥ 5887.85
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
询价
-
¥ 2883.61
-
¥ 2666.57
-
¥ 787.34
-
¥ 1476.40
-
¥ 9909.51
-
¥ 5804.96
微信小程序
7X24小时在线咨询