R-(−)-Fluoxetine hydrochloride,5MG,F1678-5MG,Sigma

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订货号 0BU8471
品牌型号 Sigma F1678-5MG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

R-(−)-Fluoxetine hydrochloride has been used as a serotonin reuptake inhibitor:

  • to study its effects on the embryoid body (EB) morphogenesis
  • in combination with muscimol hydrobromide (MUS) as well as individually to study its neurotoxic effects on neuronal cells grown on multielectrode array (MEA) chips
  • to study its effects as an endocrine disruption inducer in Pimephales promelas


Biochem/physiol Actions

Fluoxetine exhibits anti-depressant activity by increasing the serotonin levels in the neuron synaptic space. It also exhibits therapeutic effects against depression and other mood disorders.
Selective serotonin reuptake inhibitor.


Features and Benefits

This compound was developed by Eli Lilly. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


技术参数 Specifications
Quality Level100
assay>98% (HPLC)
formsolid
storage conditiondesiccated
color white
solubilityH2O: soluble >10 mg/mL
originatorEli Lilly
SMILES stringCl[H].CNCC[C@@H](Oc1ccc(cc1)C(F)(F)F)c2ccccc2
InChI1S/C17H18F3NO.ClH/c1-21-12-11-16(13-5-3-2-4-6-13)22-15-9-7-14(8-10-15)17(18,19)20;/h2-10,16,21H,11-12H2,1H3;1H/t16-;/m1./s1
InChI keyGIYXAJPCNFJEHY-PKLMIRHRSA-N
Gene Informationhuman ... HTR1A(3350), HTR1B(3351), HTR1D(3352), HTR1E(3354), HTR1F(3355), HTR2A(3356), HTR2B(3357), HTR2C(3358), HTR3A(3359), HTR3B(9177), HTR3C(170572), HTR3D(200909), HTR3E(285242), HTR4(3360), HTR5A(3361), HTR5B(645694), HTR6(3362), HTR7(3363)
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