异他林 甲磺酸盐,1G,I3639-1G,Sigma

销售价: ¥ 764.09 / 件
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订货号 0BU8764
品牌型号 Sigma I3639-1G
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Application

Isoetharine mesylate salt has been used:

  • as an adrenergic drug to test its effect on embryo implantation in 4-day pregnant mice
  • as a substrate for recombinant human sulfotransferase (SULT) in SULT assay to monitor conjugation reaction
  • as a β-2 agonist in collision-induced dissociation (CID) mass spectrometry analysis


Biochem/physiol Actions

Isoetharine is an agonist for β-adrenergic receptors and is a bronchodilator. It is a catecholic drug metabolized by sulfotransferases and is present in human urine and plasma as a sulfated metabolite. Catechol O-methyltransferase (COMT) also mediates the methylation of isoetharine in the metabolic conjugation pathway.


Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.


技术参数 Specifications
originatorSanofi Aventis
Quality Segment200
storage temp.2-8°C
SMILES stringCS(O)(=O)=O.CCC(NC(C)C)C(O)c1ccc(O)c(O)c1
InChI1S/C13H21NO3.CH4O3S/c1-4-10(14-8(2)3)13(17)9-5-6-11(15)12(16)7-9;1-5(2,3)4/h5-8,10,13-17H,4H2,1-3H3;1H3,(H,2,3,4)
InChI keySOYAGMVKMXZVNZ-UHFFFAOYSA-N
Gene Informationhuman ... ADRB1(153), ADRB2(154), ADRB3(155)
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