- 商品介绍
- 规格参数
- 包装参数
Biochem/physiol Actions
KRA-333 is a potent and selective KRAS agonist that binds directly to the GTP/GDP binding pocket of KRAS preventing the cleavage of GTP into GDP and caucusing accumulation of activated GTP-KRAS and suppression of cell growth. KRA-333 promotes apoptosis and autophagic cell death of cancer cells and inhibits growth of mutant KRAS lung cancer in xenografts mice model.
Potent and selective KRAS agonist that binds directly to the GTP/GDP binding pocket caucusing accumulation of activated GTP-KRAS and suppression of cell growth
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear |
| storage temp. | 2-8°C |
| SMILES string | O=C(O)C1=CC=C(CCCCNC(CBr)=O)C=C1 |
| InChI | 1S/C13H16BrNO3/c14-9-12(16)15-8-2-1-3-10-4-6-11(7-5-10)13(17)18/h4-7H,1-3,8-9H2,(H,15,16)(H,17,18) |
| InChI key | WZQJLTLURXNPQG-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |
-
¥ 4164.19
-
¥ 3109.49
-
¥ 8293.41
-
询价
-
询价
-
询价
-
¥ 4968.78
-
¥ 2883.61
-
¥ 4390.38
-
¥ 4404.38
-
¥ 1564.00
-
¥ 2888.88
-
¥ 64659.66
-
¥ 67162.32
-
¥ 58855.47
-
¥ 108621.02
-
询价
-
询价
-
询价
-
询价
微信小程序
7X24小时在线咨询