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Biochem/physiol Actions
Agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) that inhibit mosquito attraction to humans; potent inhibitor of myeloperoxidase (MPO)
Compound 18 is an agonist of Aedes aegypti mosquitoes NPY-like receptor 7 (NPYLR7) that inhibit mosquito attraction to humans and other hosts. Compound 18 suppresses biting and blood-feeding on a live host. Also, It (MPO-IN-28) is a potent myeloperoxidase (MPO) inhibitor with an IC50 of 44 nM.
| Quality Segment | 100 |
| assay | ≥98% (HPLC) |
| form | powder |
| color | white to beige |
| solubility | DMSO: 2 mg/mL, clear (Warmed) |
| storage temp. | -10 to -25°C |
| SMILES string | N(c1nc2c(c(n1)C)ccc(c2)OC)\C(=N\[H])\N |
| InChI | 1S/C11H13N5O/c1-6-8-4-3-7(17-2)5-9(8)15-11(14-6)16-10(12)13/h3-5H,1-2H3,(H4,12,13,14,15,16) |
| InChI key | ZJBMSSBTCGJZEE-UHFFFAOYSA-N |
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