MMP-2/MMP-9 Inhibitor I,5MG,444241-5MGCN,Sigma

销售价: ¥ 2577.98 / 件
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订货号 0BV3525
品牌型号 Sigma 444241-5MGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

A potent inhibitor of MMP-2 (IC50 = 310 nM) and MMP-9 (IC50 = 240 nM). Orally active in animal models of tumor growth and metastasis.
A potent inhibitor of MMP-2 (gelatinase A; IC50 = 310 nM) and MMP-9 (gelatinase B; IC50 = 240 nM).


Biochem/physiol Actions

Cell permeable: no
Primary Target
MMP-2, MMP-9
Product does not compete with ATP.
Reversible: no
Target IC50: 310 nM and 240 nM against MMP-2 and MMP-9


Packaging

Packaged under inert gas


Preparation Note

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.


Other Notes

Tamura, Y., et al. 1998. J. Med. Chem.41, 640.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
Quality Level100
assay≥95% (HPLC)
formsolid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze
color white
solubilityDMSO: 200 mg/mL
shipped inambient
storage temp.−20°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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