- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable trans-stilbene Resveratrol (Cat. No. 554325) analog that exhibits much enhanced anti-inflammatory potency, but no anti-oxidant activity. Suppresses LPS-induced COX-2 mRNA expression in BV-2 cells (~46% inhibition at 150 nM) and Shown to be ~130-fold more potent than Resveratrol in inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells (IC50 = 150 nM).
Biochem/physiol Actions
Cell permeable: yes
Primary Target
NF-κB Activation
Product does not compete with ATP.
Reversible: no
Target IC50: 150 nM inhibiting TNF-α-stimulated NF-κB reporter activity in 293T cells.
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 6 months at -20°C.
Other Notes
Heynekamp, J.J., et al. 2006. J. Med. Chem.49, 7182.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | crystalline solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| solubility | DMSO: 20 mg/mL |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | Fc1c(cccc1)\C=C\c2ccc(cc2)OC |
| InChI key | ILVFNAZMSMNXJG-RMKNXTFCSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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询价
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¥ 1866.29
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¥ 6330.00
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