Anti-CD62L (L-Selectin) Antibody (mouse), FITC, clone MEL-14，500UG，MABF719，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

The MEL-14 antibody is specific for mouse CD62L, also known as L-Selectin, a cell adhesion molecule which facilitates lymphocyte “rolling” on activated vascular endothelium and homing to high endothelial venules (HEV) as immune cells transmigrate from blood into peripheral tissues. L-Selectin is a member of a family of Selectin molecules which act together with the integrin family of adhesion molecules to mediate leukocyte-endothelial interactions. L-Selectin is characteristically expressed by neutrophils, and is also found on B cells, monocytes, granulocytes, and at varying levels on naive, effector and memory T cells. It is rapidly shed upon cell activation, releasing into the circulation a soluble form whose biological role is of particular interest in cancer biology research.The MEL-14 antibody may be used as a phenotypic marker for CD62L expression on a variety of immune cell types. Please note that CD62L (L-Selectin) itself is also referred to as MEL-14 in the literature.
This rat monoclonal antibody Anti-CD62L (L-Selectin) (mouse), FITC, clone MEL-14 validated for use in IP, IHC & Flow Cytometry for the detection of CD62L (L-Selectin).

Analysis Note

The monoclonal antibody was purified from tissue culture supernatant via affinity chromatography. The purified antibody was conjugated under optimal conditions, with unreacted dye removed from the preparation.

Flow Cytometry Analysis: 0.25 µg of this antibody detected CD62L (L-Selectin) in one million C57Bl/6 splenocytes.

技术参数 Specifications

biological source	rat
Quality Segment	100
conjugate	FITC conjugate
antibody form	purified antibody
antibody product type	primary antibodies
clone	MEL-14, monoclonal
species reactivity	mouse
concentration	0.5 mg/mL
technique(s)	flow cytometry: suitable,immunohistochemistry: suitable,immunoprecipitation (IP): suitable
isotype	IgG2aκ
UniProt accession no.	P18337
shipped in	wet ice
target post-translational modification	unmodified
Gene Information	mouse ... Sell(20343)

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