- 商品介绍
- 规格参数
- 包装参数
General description
一种作为DNA甲基转移酶抑制剂的胞嘧啶类似物。在TRAIL抗性细胞系中恢复caspase-8和caspase-10 mRNA和蛋白表达以及TRAIL（肿瘤坏死因子相关凋亡诱导配体）敏感性。也增强HDAC（组蛋白去乙酰化酶）抑制剂诱导的凋亡。另提供该化合物的固体形式（目录号189825）。
Packaging
用惰性气体包装
Physical form
100 mM（10 mg/438 µl）5-氮杂-2ʹ-脱氧胞苷（目录编号189825）的DMSO溶液。
Other Notes
Eggert, A., et al. 2001.Cancer Res.61, 1314.
Takebayashi, S., et al. 2001.Biochem.Biophys.Res. Commun.288, 921.
Zhu, W.G., et al. 2001.Cancer Res.61, 1327.
Hopkins-Donaldson, S., et al. 2000.Cancer Res.60, 4315.
Haaf, T. 1995.Pharmacol.Ther.65, 19.
Jones, P.A., and Taylor, S.M.1980.Cell20, 85.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：监管审查（Z）
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,desiccated (hygroscopic),protect from light |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | N2(C=NC(=N)NC2=O)C1OC(C(C1)O)CO |
| InChI | 1S/C8H12N4O4/c9-7-10-3-12(8(15)11-7)6-1-4(14)5(2-13)16-6/h3-6,13-14H,1-2H2,(H2,9,11,15) |
| InChI key | XAUDJQYHKZQPEU-UHFFFAOYSA-N |
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¥ 2814.26
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¥ 1683.78
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¥ 8520.40
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¥ 4404.38
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¥ 2268.97
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¥ 1564.00
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¥ 1749.15
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