- 商品介绍
- 规格参数
- 包装参数
General description
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle in a dose- and time-dependent manner and increases the Ca2+ permeability of SR vesicles. Useful for specific inactivation of nucleases during isolation of undegraded polynucleotides. Also inhibits platelet-activating factor acetyl hydrolase. Has been used as a probe for the topography of 5.8S rRNA in yeast ribosomes.
Biochem/physiol Actions
Cell permeable: no
Primary Target
Inhibits ryanodine binding to ryanodine/Ca2+ receptor channel in skeletal muscle
Product does not compete with ATP.
Reversible: no
Other Notes
Shoshan-Barmatz, V., and Weil, S. 1994. Biochem. J. 299, 177.
Blumbers, D.O. 1987. Methods Enzymol. 152, 20.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Harmful (C)
| Quality Level | 100 |
| description | Merck USA index - 14, 7998 |
| assay | ≥97% (titration) |
| form | liquid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | clear colorless |
| solubility | chloroform: soluble,ethanol: soluble |
| shipped in | ambient |
| storage temp. | 2-8°C |
| SMILES string | O(CC)C(=O)OC(=O)OCC |
| InChI | 1S/C6H10O5/c1-3-9-5(7)11-6(8)10-4-2/h3-4H2,1-2H3 |
| InChI key | FFYPMLJYZAEMQB-UHFFFAOYSA-N |
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¥ 2068.25
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¥ 26846.31
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