SMC® Human VEGF-A High Sensitivity Immunoassay Kit，1EACH，03-0180-00，密理博

General description

Vascular Endothelial Growth Factor A (VEGF-A) is a crucial signaling protein that promotes the growth of blood vessels (angiogenesis) in various physiological and pathological processes. It is primarily produced by endothelial cells and is involved in wound healing, embryonic development, and the response to ischemia. Elevated levels of VEGF-A are often associated with tumor growth and metastasis, making it a key target for therapeutic interventions in cancer and other diseases characterized by abnormal blood vessel formation.

Application

Inflammatory Disease / Immune Response / Autoimmune Disease

Features and Benefits

• Femtogram-Level Sensitivity for VEGF-A Detection: Enables ultrasensitive quantification of VEGF-A, critical for detecting early-stage angiogenic signaling in cancer, wound healing, and vascular disorders.
• High Specificity for VEGF-A Isoforms: No cross-reactivity with VEGF-B, VEGF-C, or VEGF-D. Ensures accurate measurement of VEGF-A, the most potent pro-angiogenic isoform, without interference from related growth factors.
• Critical Tool for Cancer and Angiogenesis Research: Enables monitoring of VEGF-A expression in tumor microenvironments, supporting studies on tumor progression, metastasis, and response to anti-angiogenic therapies.

Packaging

96 well assay

Analysis Note

• Sensitivity: LLOQ 200 fg/mL* (SMCxPRO^® Instrument)
• Standard Curve Range: 100-100,000 fg/mL
• Intra-assay CV: <15%
• Inter-assay CV: <20%
• Linearity: Serum: 106% Plasma: 105%
• Recovery: Serum: 103% Plasma: 93%

Other Notes

Although VEGF-A was detectable in non-human primate, canine and feline samples, the assay has not been verified for these species.

Legal Information

FEMTOQUEST is a trademark of Merck KGaA, Darmstadt, Germany
SMC is a registered trademark of Singulex
SMCxPRO is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.