STAT3 Inhibitor Peptide, Cell-Permeable,5MG,573096-5MGCN,Sigma

销售价: ¥ 10649.01 / 件
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订货号 0BV8286
品牌型号 Sigma 573096-5MGCN
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Supplied as a trifluoroacetate salt.
A cell-permeable analog of the Stat3-SH2 domain-binding phosphopeptide (Cat. No. 573095) that contains a C-terminal mts (membrane translocating sequence) and acts as a highly selective, potent blocker of Stat3 activation. Also suppresses constitutive Stat-3 dependent Src transformation with no effect on Stat-3 independent Ras transformation. The unphosphorylated inactive control peptide is also available under Cat. No. 573105.


Biochem/physiol Actions

Cell permeable: yes
Primary Target
Blocker of Stat3 activation
Product does not compete with ATP.
Reversible: no


Packaging

Packaged under inert gas


Other Notes

H-Pro-Tyr-(PO₃H₂)-Leu-Lys-Thr-Lys-Ala-Ala-Val-Leu-Leu-Pro-Val-Leu-Leu-Ala-Ala-Pro-OH
Turkson, J., et al. 2001. J. Biol. Chem.276, 45443.
Rojas, M., et al. 1998. Nat. Biotechnol.16, 370.


Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany


Disclaimer

Toxicity: Standard Handling (A)


技术参数 Specifications
Quality Segment100
assay≥95% (HPLC)
formlyophilized solid
manufacturer/tradenameCalbiochem®
storage conditionOK to freeze,desiccated (hygroscopic)
color white
solubilitywater: 1 mg/mL
shipped inambient
storage temp.−20°C
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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