- 商品介绍
- 规格参数
- 包装参数
General description
A cell-permeable furan carboxamide compound that acts as a potent, reversible, and ATP-competitive cFMS/CSF-1R inhibitor that blocks cFMS autophosphorylation both in CSF-1/M-CSF-stimulated HEK-293 cells (IC50 = 76 nM) and in cell-free in vitro kinase assays (IC50 = 17 nM).
Packaging
Packaged under inert gas
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Patch, R.J., et al. 2007. Bioorg. Med. Chem. Lett.17, 6070.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | yellow |
| solubility | DMSO: 5 mg/mL |
| shipped in | wet ice |
| storage temp. | −20°C |
| SMILES string | N4(CCCCC4)c1c(cc(cc1)N3CCCCC3)NC(=O)c2[o]c(cc2)C#N |
| InChI | 1S/C22H26N4O2/c23-16-18-8-10-21(28-18)22(27)24-19-15-17(25-11-3-1-4-12-25)7-9-20(19)26-13-5-2-6-14-26/h7-10,15H,1-6,11-14H2,(H,24,27) |
| InChI key | FQGXFVDABCBEFW-UHFFFAOYSA-N |
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¥ 1148.92
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¥ 2814.26
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¥ 2019.57
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¥ 1866.29
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¥ 1451.54
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¥ 9207.92
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¥ 6894.69
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¥ 2883.61
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¥ 1301.36
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