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General description
阻止肌浆网释放Ca2+的天然生物碱。对Ca2+在肌肉中的运输和作用有许多复杂的影响。纯化自兰尼碱混合物。
Biochem/physiol Actions
主要靶标
Ca2+在肌肉中的运输和作用
产物不与ATP竞争。
可逆：否
细胞可渗透性：否
Preparation Note
复溶后冷藏（4°C）。贮备溶液在4°C下可稳定保存至多1个月。
Other Notes
Sorrentino, V., and Volpe, P. 1993.Trends Pharmacol.Sci.14, 98.
Sabbadini, R., et al. 1992.J. Biol. Chem.267, 15475.
Feher, J.J., and Lipford, G.B.1985.Biochim.Biophys.Acta813, 77.
Marban, E., and Wier, W.G. 1985.Circ.Res.56, 133.
Sukto, J.L., et al. 1985.Fed.Proc.44, 2984.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性：有害（C）
| description | Merck USA index - 14, 8307 |
| Quality Level | 100 |
| assay | ≥98% (HPLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | white |
| solubility | water: 1 mg/mL,methanol: 20 mg/mL |
| shipped in | ambient |
| storage temp. | 10-30°C |
| SMILES string | [nH]1c(ccc1)C(=O)O[C@H]2[C@@]3([C@]4([C@]65O[C@]([C@]4([C@@]2(O)C(C)C)C)(C[C@]3([C@]6(CC[C@@H]([C@H]5O)C)O)C)O)O)O |
| InChI | 1S/C25H35NO9/c1-12(2)22(31)17(34-16(28)14-7-6-10-26-14)23(32)18(4)11-21(30)19(22,5)25(23,33)24(35-21)15(27)13(3)8-9-20(18,24)29/h6-7,10,12-13,15,17,26-27,29-33H,8-9,11H2,1-5H3/t13-,15+,17+,18-,19-,20-,21-,22+,23+,24+,25+/m0/s1 |
| InChI key | JJSYXNQGLHBRRK-YSOSZROBSA-N |
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¥ 9737.84
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¥ 39676.71
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