- 商品介绍
- 规格参数
- 包装参数
General description
A potent, reversible inhibitor of granzyme B and caspase-8 (Ki = 1 nM). Also inhibits caspase-1 (<6 nM), caspase-6 (5.6 nM), and caspase-10 (27 nM).
Potent, reversible granzyme B and caspase-8 inhibitor.
Biochem/physiol Actions
Cell permeable: no
Product does not compete with ATP.
Reversible: yes
Target Ki: 1 nM against caspase-8
Other Notes
Ac-Ile-Glu-Thr-Asp-CHO
Gao, C.F., et al. 2001. Exp. Cell. Res.265, 145.
Garcia-Calvo, M., et al. 1998. J. Biol. Chem.273, 32608.
Han, Z., et al. 1997. J. Biol. Chem. 272, 13422.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| Quality Segment | 100 |
| assay | ≥95% (HPLC) |
| form | lyophilized solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | white |
| solubility | DMSO: 1 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | N([C@@H]([C@@H](O)C)C(=O)N[C@@H](CC(=O)O)C=O)C(=O)[C@@H](NC(=O)[C@@H](NC(=O)C)[C@H](CC)C)CCC(=O)O |
| InChI key | AXTKTZHLZLOIIO-WBOIFEBMSA-N |
| 长度(mm) | |
| 宽度(mm) | |
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| 重量(kg) |
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¥ 4164.19
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¥ 2290.21
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¥ 2814.26
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¥ 2013.69
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¥ 1451.54
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¥ 2068.25
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¥ 4173.75
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¥ 1956.41
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¥ 3152.47
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¥ 3372.68
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¥ 4968.78
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¥ 3335.66
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¥ 1564.00
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