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General description
A useful agent for introducing thiol groups, in protected form, into various proteins. Reacts with primary amines to add protected sulfhydryl groups. When treated with hydroxylamine, yields a free sulfhydryl group that can be conjugated to maleimide-modified proteins.
Preparation Note
Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 3 months at -20°C.
Other Notes
Duncan, R.J., et al. 1983. Anal. Biochem.132, 68.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
Toxicity: Standard Handling (A)
| assay | ≥98% (HPLC) |
| Quality Level | 100 |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze |
| color | white |
| solubility | DMSO: 10 mg/mL |
| shipped in | ambient |
| storage temp. | −20°C |
| SMILES string | S(CC(=O)ON1C(=O)CCC1=O)C(=O)C |
| InChI | 1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3 |
| InChI key | FLCQLSRLQIPNLM-UHFFFAOYSA-N |
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