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- 规格参数
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General description
苯乙胺衍生物。一种刺激腺苷酸环化酶活性的选择性β-肾上腺素能激动剂。促进糖原分解并引起支气管扩张。通过产生一氧化氮增加兔气管细胞中Cl–的扩散和电位差。据报道,通过Rap1和B-Raf依赖性过程激活MAP激酶(ERK)。
Biochem/physiol Actions
主要靶标
β肾上腺素能激动剂
产物不与ATP竞争。
可逆:否
细胞渗透性:否
Preparation Note
溶液中不稳定;仅在使用前进行复溶。
Other Notes
Schmitt, J.M., and Stork, P.J.2000.J. Biol. Chem.275, 25342.
Carmena, M.J., et al. 1997.Prostate 33, 46.
Takemura, H., et al. 1995.J. Pharmacol.Exp.Ther.274, 584.
Kishimoto, I., et al. 1994.J. Biol. Chem.269, 28300.
Macaulay, S.L., et al. 1994.Mol.Cell Biochem.141, 27.
Yashiro, K., et al. 1994.J. Biochem.115, 1040.
Ladenheim, R.G., et al. 1993.J. Neurochem.60, 260.
von Zastrow, M., et al. 1993.J. Biol. Chem.268, 763.
Mokhtari, A., et al. 1985.J. Cyclic Nucleotide Protein Phosphorylation Res.10, 213.
Legal Information
CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany
Disclaimer
毒性:刺激性(B)
| description | Merck USA index - 14, 5217 |
| Quality Level | 100 |
| assay | ≥99% (TLC) |
| form | solid |
| manufacturer/tradename | Calbiochem® |
| storage condition | OK to freeze,protect from light |
| color | white to off-white, white |
| solubility | ethanol: soluble,water: soluble |
| shipped in | ambient |
| storage temp. | 10-30°C |
| SMILES string | [Cl-].N(C(C)C)CC(O)c1cc(c(cc1)O)O.[H+] |
| InChI | 1S/C11H17NO3.ClH/c1-7(2)12-6-11(15)8-3-4-9(13)10(14)5-8;/h3-5,7,11-15H,6H2,1-2H3;1H |
| InChI key | IROWCYIEJAOFOW-UHFFFAOYSA-N |
| 长度(mm) | |
| 宽度(mm) | |
| 高度(mm) | |
| 重量(kg) |





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