Anti-CCR7 antibody produced in rabbit,100UL,SAB5700867-100UL,Sigma

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订货号 0BL1469
品牌型号 Sigma SAB5700867-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

The protein encoded by this gene is a member of the G protein-coupled receptor family. This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. This receptor is expressed in various lymphoid tissues and activates B and T lymphocytes. It has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. Signals mediated by this receptor regulate T cell homeostasis in lymph nodes, and may also function in the activation and polarization of T cells, and in chronic inflammation pathogenesis. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2014]


Immunogen

A synthesized peptide derived from human CCR7


Physical form

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody product typeprimary antibodies
clonemonoclonal
formliquid
species reactivityhuman, rat, mouse
concentration1.55 mg/mL
technique(s)immunohistochemistry: 1:50-1:200,western blot: 1:500-1:2000
UniProt accession no.P32248
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CCR7(1236)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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