Anti-H1N1 Neuraminidase antibody produced in rabbit,100UG,SAB3501250-100UG,Sigma

销售价: ¥ 4150.58 / 件
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订货号 0BL1478
品牌型号 Sigma SAB3501250-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

H1N1 Neuraminidase Antibody: Influenza A virus is a major public health threat, killing more than 30, 000 people per year in the USA. In early 2009, a novel swine-origin influenza A (H1N1) virus was identified in specimens obtained from patients in Mexico and the United States. The virus spread quickly around the world and on June 11, 2009, the World Health Organization declared it a pandemic. Influenza A virus has one of sixteen possible Hemagglutinin (HA) surface proteins and one of nine possible Neuraminidase (NA) surface proteins. The Hemagglutinin protein facilitates viral attachment while Neuraminidase is involved in viral release. These proteins also elicit immune responses that prevent infection or independently reduce viral replication. The genetic make-up of this swine flu virus is unlike any other: it is an H1N1 strain that combines a triple assortment first identified in 1998 including human, swine, and avian influenza with two new pig H3N2 virus genes from Eurasia, themselves of recent human origin. The distinct antigenic properties of the new swine influenza virus compared with seasonal influenza A (H1N1) virus suggest that human immunity against new swine influenza virus is limited, although the age distribution of reported cases suggests some degree of protection in older age groups.


Immunogen

Neuraminidase antibody was raised against synthetic peptides from the seasonal influenza (H1N1) Neuraminidase protein and the novel swine influenza Neuraminidase protein.The antibody recognizes both variants.The immunogen is located within the first 50 amino acids of H1N1 Neuraminidase.


Application

Neuraminidase antibody can be used for the detection of the Neuraminidase protein from the seasonal influenza A (H1N1) and the novel swine influenza in ELISA. It will detect 2 ng of free peptide at 1 μg/mL.


Physical form

Supplied in PBS containing 0.02% sodium azide.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity isolated antibody
antibody product typeprimary antibodies
clonepolyclonal
formliquid
species reactivityInfluenza A virus subtype H1N1
concentration1 mg/mL
technique(s)ELISA: suitable
isotypeIgG
UniProt accession no.B1AGS8,C4AL28
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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