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General description
UNG2 (uracil-DNA glycosylase) is a multifunctional glycosylase,that is located in the nucleus. It is also known as CCNO (cyclin O)and is located on chromosome 5q11. It is present in the apical cytoplasm of multiciliated cells.
Immunogen
a 14 amino acid peptide from near the amino-terminus of human UNG2.
Biochem/physiol Actions
CCNO (cyclin O) is responsible for the differentiation of multiciliated cell. It participates in the cell cycle and DNA repair. CCNO mutations cause congenital mucociliary clearance disorder. It is considered as an important enzyme in base excision repair (BER).
Physical form
Solution in phosphate buffered saline containing 0.02% sodium azide
Other Notes
The action of this antibody can be blocked using blocking peptide SBP3859.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | predicted mol wt 39 kDa |
| species reactivity | rat, human, mouse |
| technique(s) | indirect ELISA: suitable,western blot: suitable |
| UniProt accession no. | P22674 |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... CCNO(10309) |
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¥ 4173.75
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¥ 8293.41
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¥ 5167.58
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¥ 1653.62
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¥ 4897.21
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¥ 8982.64
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¥ 2882.02
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¥ 2406.69
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¥ 1351.48
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