Monoclonal Anti-CDC25B antibody produced in mouse,100UG,WH0000994M1-100UG,Sigma

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订货号 0BL1709
品牌型号 Sigma WH0000994M1-100UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

CDC25B is a member of the CDC25 family of phosphatases. CDC25B activates the cyclin dependent kinase CDC2 by removing two phosphate groups and it is required for entry into mitosis. CDC25B shuttles between the nucleus and the cytoplasm due to nuclear localization and nuclear export signals. The protein is nuclear in the M and G1 phases of the cell cycle and moves to the cytoplasm during S and G2. CDC25B has oncogenic properties, although its role in tumor formation has not been determined. Multiple transcript variants for this gene exist. (provided by RefSeq)


Immunogen

CDC25B (NP_068660, 181 a.a. ~ 280 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
VRFWKAGVGALREEEGACWGGSLACEDPPLPSWLQDGFVFKMPWKPTHPSSTHALAEWASRREAFAQRPSSAPDLMCLSPDRKMEVEELSPLALGRFSLT


Physical form

Solution in phosphate buffered saline, pH 7.4


Legal Information

GenBank is a registered trademark of United States Department of Health and Human Services


技术参数 Specifications
biological sourcemouse
Quality Level100
conjugateunconjugated
antibody formpurified immunoglobulin
antibody product typeprimary antibodies
clone7E8, monoclonal
formbuffered aqueous solution
species reactivityhuman
technique(s)indirect ELISA: suitable,western blot: 1-5 μg/mL
isotypeIgG1κ
GenBank accession no.NM_021874
UniProt accession no.P30305
shipped indry ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... CDC25B(994)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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