SMYD2, GST tagged human,20UG,SRP5257-20UG,Sigma

销售价: ¥ 2679.16 / 件
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订货号 0BL2217
品牌型号 Sigma SRP5257-20UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

SMYD2 (also known as SET and MYND domain-containing protein 2) is a member of the SMYD family of protein methyltransferases. SMYD2 is also known as lysine methyltransferase protein 3C (KMT3C). SMYD2 functions to repress transcription by interacting with the Sin3A histone deacetylase complex and performs methylation of Lys36 in histone H3. The exogenous expression of SMYD2 in mouse fibroblasts decreases cell growth. SMYD2 also function as a putative oncogene by methylating p53 and repressing its tumor suppressive function.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.


Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
mol wt ~70 kDa
NCBI accession no.BC049367
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... SMYD2(56950)
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