PIK3C2A, active, GST tagged human,10UG,SRP5330-10UG,Sigma

销售价: ¥ 3866.08 / 件
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订货号 0BL4108
品牌型号 Sigma SRP5330-10UG
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

PIK3C2A is belongs to the phosphoinositide 3-kinase (PI3K) family which play roles in signaling pathways involved in cell proliferation, oncogenic transformation, cell survival, cell migration, and intracellular protein trafficking. PIK3C2A can phosphorylate phosphatidylinositol and phosphatidylinositol-4-phosphate in vitro. PIK3C2A contains a lipid kinase catalytic domain as well as a C-terminal C2 domain, a characteristic of class II PI3-kinases that act as calcium-dependent phospholipid binding motifs that mediate translocation of proteins to membranes, and may also mediate protein-protein interactions.


Physical form

Supplied in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.


Preparation Note

After opening, aliquot into smaller quantities and store at -70 °C. Avoid repeating handling and multiple freeze/thaw cycles.


Legal Information

PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany


技术参数 Specifications
recombinantexpressed in baculovirus infected Sf9 cells
product linePRECISIO®
assay≥70% (SDS-PAGE)
formbuffered aqueous glycerol solution
specific activity16.2-25.3 nmol/min·mg
mol wt ~155 kDa
NCBI accession no.NM_002645
shipped indry ice
storage temp.−70°C
Gene Informationhuman ... PIK3C2A(5286)
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