- 商品介绍
- 规格参数
- 包装参数
General description
G protein-coupled receptor 40 (GPR40) belongs to the G protein-coupled receptors. It is a 300 amino acid protein, that has seven characteristic transmembrane domains. GPR40 is also known as FFA1 (free fatty acid receptor 1). It is expressed in the β cell of the pancreas, spinal cord and brain. It is located on human chromosome 19q13.
Immunogen
Peptide with sequence CAARTQGGKSQK from the C Terminus of the protein sequence according to NP_005294.1.
Biochem/physiol Actions
G protein-coupled receptor 40 (GPR40) maintains insulin and glucose homeostasis. It plays an important role in the development of type 2 diabetes. GPR40/FFA1 signaling may participate in the regulation of endogenous pain control systems. It is considered as an anti-diabetic drug target.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Supplied at 0.5 mg/mL in Tris saline with 0.02% sodium azide and 0.5% bovine serum albumin.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | goat |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| species reactivity | human |
| technique(s) | indirect ELISA: suitable,western blot: suitable |
| shipped in | dry ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... GPR40(2864) |
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