- 商品介绍
- 规格参数
- 包装参数
General description
Receptor interacting serine/threonine kinase 2 (RIPK2) or RICK is a serine/threonine kinase. It contains a kinase domain at the amino-terminal, an intermediate domain and a caspase activation and recruitment domain (CARD) at the carboxy-terminal. The gene encoding RIPK2 is localized on human chromosome 8q21.3.
Biochem/physiol Actions
Receptor interacting serine/threonine kinase 2 (RIPK2) or RICK is activated during innate immune responses and acts as a scaffold for downstream effectors. It functions in nuclear factor-κB (NFκB) activation pathways. The protein also has roles in toll-like receptor (TLR)-signaling pathways and in the production of inflammatory cytokines.
Physical form
Supplied in 50 mM Tris-HCl, pH 7.5, with 150 mM NaCl, 0.2 5mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, and 25% glycerol.
Legal Information
PRECISIO is a registered trademark of Merck KGaA, Darmstadt, Germany
| recombinant | expressed in baculovirus infected Sf9 cells |
| Quality Level | 200 |
| product line | PRECISIO® Kinase |
| assay | ≥70% (SDS-PAGE) |
| form | buffered aqueous glycerol solution |
| specific activity | 17-23 nmol/min·mg |
| mol wt | ~59 kDa |
| UniProt accession no. | O43353 |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... RIPK2(8767) |
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¥ 2707.32
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¥ 2622.09
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¥ 1563.36
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¥ 1724.25
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¥ 8520.40
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¥ 10277.12
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¥ 2882.02
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¥ 1196.00
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¥ 787.34
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¥ 2277.64
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¥ 3404.94
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