Anti-ACTN2 Antibody, clone 2P7E6, Rabbit Monoclonal,100UL,SAB5702618-100UL,Sigma

销售价: ¥ 3636.13 / 件
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订货号 0BL6368
品牌型号 Sigma SAB5702618-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

General description

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]


Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACTN2 (P35609).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.


Application

WB, IF/ICC


技术参数 Specifications
biological sourcerabbit
Quality Level100
materialcolorless
clone2P7E6, monoclonal
formliquid
mol wt 104 kDa
species reactivityrat, human
concentration0.34 mg/mL
technique(s)immunofluorescence: 1:50 - 1:200,western blot: 1:500 - 1:2000
color colorless
isotypeIgG
immunogen sequenceMNQIEPGVQYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANV
UniProt accession no.P35609
shipped inwet ice
storage temp.−20°C
target post-translational modificationunmodified
Gene Informationhuman ... ACTN2(88)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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