Monoclonal Anti-IFIH1 antibody produced in mouse，100UG，SAB1402619-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein that is upregulated in response to treatment with beta-interferon (IFNB) and a protein kinase C-activating compound, mezerein (MEZ). Irreversible reprogramming of melanomas can be achieved by treatment with both these agents; treatment with either agent alone only achieves reversible differentiation. (provided by RefSeq)

Immunogen

IFIH1 (NP_071451.2, 928 a.a. ~ 1023 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
HVNMTPEFKELYIVRENKALQKKCADYQINGEIICKCGQAWGTMMVHKGLDLPCLKIRNFVVVFKNNSTKKQYKKWVELPITFPNLDYSECCLFSD

Physical form

Solution in phosphate buffered saline, pH 7.4

技术参数 Specifications

biological source	mouse
Quality Level	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	3F6, monoclonal
form	buffered aqueous solution
mol wt	antigen ~36.67 kDa
species reactivity	human
technique(s)	immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable,indirect ELISA: suitable
isotype	IgG2aκ
NCBI accession no.	NM_022168
UniProt accession no.	Q9BYX4
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... IFIH1(64135)

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