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- 规格参数
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General description
The Forkhead Box L1 (FoxL1) is a transcription factor that modulates epithelial growth and gastrointestinal development. This transcription factor has been implicated in pancreatic and gastrointestinal carcinogenesis and can also function as prognostic biomarker for clear cell renal cell carcinoma. Studies in mce have also revealed that FoxL1 can function as a biological marker of the hepatic progenitor cells.
Rabbit Anti-FOXL1 antibody recognizes canine, human, and mouse FOXL1.
Immunogen
Synthetic peptide directed towards the N terminal region of human FOXL1
Application
Rabbit Anti-FOXL1 antibody can be used for western blot (2.5μg/ml) and IHC (4-8μg/ml) assays.
Biochem/physiol Actions
FOXL1 is a member of the forkhead family. The forkhead domain is a monomeric DNA binding motif that defines a rapidly growing family of eukaryotic transcriptional regulators. Genetic and biochemical data suggest a central role in embryonic development for forkhead proteins.
Physical form
Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Other Notes
Synthetic peptide located within the following region: HLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPY
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | IgG fraction of antiserum |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | 36 kDa |
| species reactivity | bovine, horse, human, pig, dog |
| concentration | 0.5 mg - 1 mg/mL |
| technique(s) | immunohistochemistry: suitable,western blot: suitable |
| web metadata keyword.default | Anti-FOXL1 antibody for clear cell renal cell carcinoma,Anti-FOXL1 antibody for immunofluorescence applications,Anti-Forkhead box L1 antibody for western blot,Canine FOXL1 antibody for veterinary research,FOXL1 antibody for hepatic progenitor cell research,FOXL1 antibody rabbit for immunohistochemistry,FOXL1 antibody sc-130373 for lab use,FOXL1 rabbit polyclonal antibody 100µg,FOXL1 transcription factor antibody for cancer research,High purity Rabbit Anti-FOXL1 antibody,Mouse FOXL1 antibody for comparative studies,Rabbit Anti-FOXL1 antibody Sigma-Aldrich,Rabbit Anti-FOXL1 antibody for pancreatic cancer studies,Rabbit Anti-FOXL1 antibody,Rabbit polyclonal antibody against FOXL1 |
| NCBI accession no. | NP_005241 |
| UniProt accession no. | Q12952 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... FOXL1(2300) |
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