Anti-MATN1 antibody produced in rabbit，100UG，SAB3500034-100UG，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

Matrilins (MATNs) are a family of non-collagenous extra-cellular matrix (ECM) proteins consisting of four known members that have been proposed to play key roles in modulating cellular phenotypes during chondrogenesis of mesenchymal stem cells (MSCs). MATN1 and MATN3 are expressed specifically in cartilage and are among the most up-regulated ECM proteins during chondrogenesis. MATN1 is composed of two Willebrand Factor A (vWFA) domains separated by one EGF-like domain, whereas MATN3 is composed of a single N-terminal vWFA domain followed by four epidermal growth factor (EGF) repeats and a coiled-coil domain. MATN1 or MATN3 may play a role in modulating chondrogenesis during the chondrocyte differentiation process. Mutations of this gene have been associated with variety of inherited chondrodysplasias. Recent studies show that the MATN1 promoter region was associated with both susceptibility and disease progression in Adolescent idiopathic scoliosis.

Immunogen

MATN1 antibody was raised against a 13 amino acid peptide from near the carboxy terminus of human MATN1.

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

Other Notes

The action of this antibody can be blocked using blocking peptide SBP3500034.

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	affinity isolated antibody
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
species reactivity	mouse, rat, human
technique(s)	immunofluorescence: suitable,immunohistochemistry: suitable,indirect ELISA: suitable,western blot: suitable
NCBI accession no.	NP_002370
UniProt accession no.	P21941
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... MATN1(4146)

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