- 商品介绍
- 规格参数
- 包装参数
General description
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
Immunogen
A synthesized peptide derived from human LRP1
Physical form
Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody product type | primary antibodies |
| clone | monoclonal |
| form | liquid |
| species reactivity | rat, human, mouse |
| concentration | 0.23 mg/mL |
| technique(s) | western blot: 1:500-1:2000 |
| UniProt accession no. | Q07954 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... LRP1(4035) |
| 长度(mm) | |
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| 重量(kg) |
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¥ 12156.68
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¥ 2019.57
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¥ 2068.25
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¥ 4039.86
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¥ 1724.25
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¥ 3442.25
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¥ 3275.78
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¥ 238.17
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¥ 8982.64
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¥ 1476.00
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