Anti-Human IgG (Fc specific)-Peroxidase antibody, Mouse monoclonal，1VIAL，SAB4200790-1VL，Sigma 供应商、价格、厂家、报价、规格参数

产品介绍 Product Description

General description

IgGs are the most common Immunoglobulins isotype in blood, lymph fluid, cerebrospinal fluid, and peritoneal fluid and a key players in the humoral immune response. IgGs include four subclasses (IgG1, IgG2, IgG3, and IgG4), they consist of a variable Fab fragment (which includes the antibody recognition site), and a conserved Fc fragment. The IgG subclasses differ in their physical and chemical properties, their distribution pattern is found to be age-dependent and every subclass has a specific biological function. IgG deficiencies are often associated with various diseases.

The Fc fragment has various important functions such as complement fixation, site for rheumatoid factor (autoantibody directed to Fc) attachment, passage through the placental membrane and protein A binding. A certain population of lymphocytes also possess an "Fc receptor". These functions indicate the importance of immunoreagents specific for the Fc fragment of Human IgG.

Monoclonal Anti-Human IgG (Fc specific) is specific for the Fc fragment of Human IgG and is observed with all human IgG subclasses but not with the Fab fragment of human IgG, purified light chains, human IgA or human IgM.

Immunogen

Purified human IgG myeloma proteins covalently coupled to polyaminostyrene (PAS) microbeads.

Application

The antibody is recommended to use in various immunological techniques, including ELISA.

Physical form

Supplied as a lyophilized powder

Other Notes

This product is for R&D use only, not for drug, household, or other uses.

技术参数 Specifications

biological source	mouse
Quality Level	200
conjugate	peroxidase conjugate
antibody form	purified from hybridoma cell culture
antibody product type	primary antibodies
clone	GG-7, monoclonal
form	lyophilized powder
species reactivity	human
technique(s)	direct ELISA: 1:40,000-1:80,000 using 2.5 μg/mL human IgG1 for coating
isotype	IgG1
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified

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