Rabbit anti-Chk1 Antibody, Affinity Purified,100UL,PLA0085-100UL,Sigma

销售价: ¥ 4577.66 / 件
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订货号 0BM2508
品牌型号 Sigma PLA0085-100UL
货期 询货期
最小订货量 1件
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产品介绍 Product Description

Immunogen

The epitope recognized by PLA0085 maps to a region between residues 250 and 300 of human Checkpoint Kinase 1 using the numbering given in SwissProt entry O14757 (GeneID 1111).


Physical form

Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09% Sodium Azide


Other Notes

Chk1 functions as a checkpoint protein kinase that is critical to the regulation of the Cdc25a and Cdc25c phosphatases that promote S and G2/M phase progression, respectively. Chk1 kinase activity inhibits cell cycle progression in the presence of DNA damage by phosphorylating Cdc25a and Cdc25c and causing the degradation of Cdc25a and cytoplasmic sequestration of Cdc25c.


Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.


技术参数 Specifications
biological sourcerabbit
Quality Level100
conjugateunconjugated
antibody formaffinity purified immunoglobulin
antibody product typeprimary antibodies
clonepolyclonal
species reactivityhuman
technique(s)immunohistochemistry: 1:1,000- 1:5,000,immunoprecipitation (IP): 2-10 μg/mg,western blot: 1:1,000-1:5,000
accession no.O14757
shipped inwet ice
storage temp.2-8°C
target post-translational modificationunmodified
Gene Informationrabbit ... Chk1(1111)
长度(mm)
宽度(mm)
高度(mm)
重量(kg)
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