Anti-CYP27A1 antibody produced in rabbit，100UG，SAB1410281-100UG，Sigma

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订货号： 0BM2663

品牌型号： Sigma SAB1410281-100UG

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最小订货量： 1件

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产品介绍 Product Description

General description

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein oxidizes cholesterol intermediates as part of the bile synthesis pathway. Since the conversion of cholesterol to bile acids is the major route for removing cholesterol from the body, this protein is important for overall cholesterol homeostasis. Mutations in this gene cause cerebrotendinous xanthomatosis, a rare autosomal recessive lipid storage disease. (provided by RefSeq)

Immunogen

CYP27A1 (NP_000775.1, 1 a.a. ~ 531 a.a) full-length human protein.

Sequence
MAALGCARLRWALRGAGRGLCPHGARAKAAIPAALPSDKATGAPGAGPGVRRRQRSLEEIPRLGQLRFFFQLFVQGYALQLHQLQVLYKAKYGPMWMSYLGPQMHVNLASAPLLEQVMRQEGKYPVRNDMELWKEHRDQHDLTYGPFTTEGHHWYQLRQALNQRLLKPAEAALYTDAFNEVIDDFMTRLDQLRAESASGNQVSDMAQLFYYFALEAICYILFEKRIGCLQRSIPEDTVTFVRSIGLMFQNSLYATFLPKWTRPVLPFWKRYLDGWNAIFSFGKKLIDEKLEDMEAQLQAAGPDGIQVSGYLHFLLASGQLSPREAMGSLPELLMAGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKDFAHMPLLKAVLKETLRLYPVVPTNSRIIEKEIEVDGFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLRNSQPATPRIQHPFGSVPFGYGVRACLGRRIAELEMQLLLARLIQKYKVVLAPETGELKSVARIVLVPNKKVGLQFLQRQC

Physical form

Solution in phosphate buffered saline, pH 7.4

技术参数 Specifications

biological source	rabbit
Quality Level	100
conjugate	unconjugated
antibody form	purified immunoglobulin
antibody product type	primary antibodies
clone	polyclonal
form	buffered aqueous solution
mol wt	antigen 60.2 kDa
species reactivity	human
technique(s)	western blot: 1 μg/mL
NCBI accession no.	NM_000784.2
UniProt accession no.	Q02318
shipped in	dry ice
storage temp.	−20°C
target post-translational modification	unmodified
Gene Information	human ... CYP27A1(1593)

长度(mm)
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