- 商品介绍
- 规格参数
- 包装参数
General description
The EMCN (endomucin) gene is mapped to human chromosome 4q24. It encodes a 80−120kDa transmembrane sialomucin. Mucin-14 is predominantly expressed in heart, kidney and lungs. Endomucin is a surface glycoprotein localized to the endothelial cells. Mucin-14 is a type 1 integral protein. Endomucin possesses 261 amino acid residues and a serine/threonine-rich extracellular domain. Anti-Mucin-14 Antibody detects endogenous levels of total Mucin-14 protein.
Immunogen
The antiserum was produced against synthesized peptide derived from human Mucin-14.
Immunogen Range: 201-250
Biochem/physiol Actions
Mucin-14 controls lymphocyte adhesion and its expression is associated with the pathogenesis of rheumatoid arthritis. Mucin-14 associated with O-glycans enables it to promote cell−matrix and cell-cell interactions.
Features and Benefits
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
Physical form
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Disclaimer
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
| biological source | rabbit |
| Quality Level | 100 |
| conjugate | unconjugated |
| antibody form | affinity isolated antibody |
| antibody product type | primary antibodies |
| clone | polyclonal |
| form | buffered aqueous solution |
| mol wt | antigen 27 kDa |
| species reactivity | human, rat, mouse |
| concentration | ~1 mg/mL |
| technique(s) | ELISA: 1:1000,immunofluorescence: 1:100-1:500 |
| NCBI accession no. | Q9ULC0 |
| UniProt accession no. | Q9ULC0 |
| shipped in | wet ice |
| storage temp. | −20°C |
| target post-translational modification | unmodified |
| Gene Information | human ... EMCN(51705) |
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